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for youths given the chemical over several days. But Pelphrey said oxytocin might help the brain learn from social interactions; it would work best when used with therapies that encourage people with autism to engage more socially, he said. “Our study shows that oxytocin affects the brain and opens up the possibility that, when combined with behavioural treatments, it works like a social enhancer,” he said. The scientists used a technique called functional MRI to scan the brains of 17 youths aged eight to 16 with autism while they looked at images of cars or the eyes of people expressing various emotions. The scans were given 45 minutes after the participants inhaled a placebo or oxytocin through a nasal spray. The scans showed that reward circuitry in the childrens brains behaved more normally after a snort of oxytocin, being more active when the person was looking at faces and less active when viewing the inanimate cars. The study appears in the latest issue of the journal Proceedings of the National Academy of Sciences in the United States. “If this is replicated, it suggests that oxytocin might treat something for which we dont have a treatment in autism, and thats the core social motivation,” Pelphrey told the Guardian. He warned that it was too early to use oxytocin as a treatment for the social difficulties caused by autism and cautioned against

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August 2026